Supplement Questions

ExRx.net > Questions > Q&A

I am in my mid 40s and have not been seeing much progress in the gym. Someone suggested I should consider using MGF . I looked up "MGF supplement" on Google and found alot of information. Please let me know what you think of it.

Dr Eric Serrano, M.D. found no significant increase of growth hormone with MGF spray in his clinical studies. Dr. Serrano has noted a significant increase of growth hormone with 8 to 12 grams of arginine pyroglutamate but he warns some people get nauseated.

Amino acids, such as Arginine and Orthinine may increase growth hormone, but it has been proposed a stress to the body, such as irritation to the gastro-intestinal system can increase growth hormone. Interestly, workouts with only a brief rest between sets and exercises can increase growth hormone.

The effects of growth hormone in adults seem to be more lipolytic than anabolic. In other words, an increase of growth hormone may burn fat more than build muscle.


Would you recommend 1-AD (Androgen-1). It contains 1 (5-alpha) Androstene 3, 17 diol 100mg. The label says: "The Anabolic platform from IDS is made up of prohormones which primarily effect muscle tissue similar to Deca Durabolin, Anavar, or Primabolin."

Dr Eric Seranno, MD explains this prehormone is a very active compound, and even though Androstene supposedly does not metabolize to estrogen directly it will affect estrogens receptors. He suggests you would be better of spending your money on steroids and get better results with the same side effects. Dr. Serrano explains:

"In my clinic, 90% of the people that use prohormones for a long time will get some type of mental problem, depression, anxiety, something, that is why I don't recommend them".

Serrano feels the manufactures and resalers of these supplements have been less than honest toward consumers about how well these componds work. He does see results with some of his patients within 6 weeks, increasing in size and strength, but after there is no additional progress. Serrano suggests if someone insists on using prehormones, they consider using them 6 weeks on and three weeks off.

Dr Mauro Di Pasquale, MD also points out problems with the use of prohormone:

    • Any increase in androgen / testosterone formation decreases testicular steroidogenesis
      • possible lower testosterone levels as HPTA becomes refractory
    • Estrogen and DHT formation
    • Potential adverse effects
    • Positive drug test

Dr. Di Pasquale concludes:

"Prehormones are too big of market to let go. We will see many variations of them in the future."

Update: The US Government has recently enacted law prohibiting the sale of prehormones supplements.

 

Main Menu | Dietary Supplements | Nutrition Titles